Sinister Six (Earth-7045)

The Sinister Six is a group of supervillains who periodically come together for revenge against Spider-Man, being consistently composed of his rogues gallery. The final incarnation led by the Green Goblin is also known as Osborn's Six.

History
to be added

First & Third

 * Doctor Octopus (leader)
 * Electro
 * Kraven the Hunter
 * Mysterio
 * Sandman
 * Vulture

Second

 * Doctor Octopus (leader)
 * Electro
 * Hobgoblin (Jason Macendale, Jr.)
 * Mysterio
 * Sandman
 * Vulture

Fourth (Osborn's Six)

 * Green Goblin (leader)
 * Chameleon
 * Lizard (unwillingly)
 * Mysterio
 * Scorpion
 * Venom