Ophelia Sarkissian (Earth-1600)

"Attention all security staff, this is Madame Hydra! It seems my little pets are escaping their pens. All long-range units converge on the eastern rail bridge. The rest of you... KILL THE SUPER SOLDIER!"

- Madame Hydra Ophelia Sarkissian (a.k.a. Madame Hydra) is a lieutenant of the terrorist organization, Hydra.